Can Dietary Supplements Affect the Depo Shot?

Drug interactions are a serious problem that can lead to lasting health effects, so every time you start a new drug treatment, you have to carefully examine any medication you have taken without causing problems. The same is true of dietary supplements, because both drugs and supplements affect how your body uses the substances you consume; for example, taking St. John's wort may affect the contraceptive pill. However, depo Provera seems to interact less.